PCI – 7th June 2024
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Comparing Organoids and Patient-derived Xenograft Models for the Development of Antibody-drug Conjugates

Antibody-drug conjugates (ADCs) are one of the most rapidly expanding forms of oncology treatment and therapeutic successes have led to an unprecedented expansio...
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Benefits of Mass Spectrometry from Process Development to GMP Release of Biomolecules – A Comprehensive CDMO Perspective from Richter BioLogics

In biopharmaceutical production, a thorough understanding of analytical processes and target molecules is essential for ensuring patient safety, as well as maint...
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Lipid Nanoparticles (LNPs) for Nucleic Acid Delivery 

Lipid nanoparticles (LNPs) are one of the most prominent tools for nucleic acid delivery. Their versatility allows the encapsulation of different cargos (siRNA, ...
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Accelerating Cell Line Selection with Integrated Analytical Strategies

Cell line development is a critical determinant of success in biologics manufacturing. It lays the foundation for product yield, quality and long-term process st...
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Leveraging Strategic Partnerships to Enhance Flexibility in Facility Design and Bioprocesses

Flexibility is an operational imperative in today’s fast-evolving biopharmaceutical industry. Contract development and manufacturing organisations (CDMOs), as in...
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Scale-up Evaluation of the DynaDrive S.U.B.s

Part 3: Pilot and Manufacturing Scale Comparison of DynaDrive S.U.B. Capabilities Introduction Commercialisation of a drug is a monumental milestone that h...
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Turning the Temperature Up on Cold Chain Logistics

As biopharma therapies become more sensitive, costly and complex, traditional compliance frameworks are no longer enough. Real-time visibility and IoT innovation...
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Developing Endotoxin Limits, Risk Assessment and In-process Testing for CGT Products

Cell & Gene Therapy (CGT) products face a unique challenge in the required pyrogen testing for injectable wares. Since this test was written for conventional...
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Use of the aProximateTM ProximalTubule Cell Model for the Evaluation of Safety and RenalAccumulation of Radioconjugates and Large Molecules

The aProximateTM Proximal Tubule Cell (PTC) model offers a cutting-edge platform for the evaluation of drug-induced nephrotoxicity, radioconjugate retention and ...
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