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FDA, as expected, rejects Lilly and Innovent immunotherapy in signal to drugmakers

Dive Brief: The Food and Drug Administration has rejected an experimental cancer immunotherapy Eli Lilly and partner Innovent Biologics have been developing for a ...
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J&J to explore RNA reprogramming with Remix research deal

Dive Brief: Johnson & Johnson is partnering with Remix Therapeutics to develop drugs that are meant to reprogram how RNA is processed, becoming the latest big ...
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After years of decline, drugmakers’ price hikes may have bottomed out

Double-digit list price increases for branded medicines in the middle of the last decade put drugmakers in political crosshairs. Under criticism and pressure, those b...
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Latest Roche results show promise for new type of cancer immunotherapy

Though drugmakers have spent considerable resources trying to expand the reach of immunotherapy through new drug combinations, success has been hard to find. Multiple...
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Blueprint, taking aim at larger drugmakers, becomes a biotech buyer

Lengo's drug targets a mutation in the gene that drives production of a protein called EGFR, which, in turn, can help spur tumor growth. The mutation, found in the ex...
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Vaccine makers move quickly to confront omicron threat

Several companies, including Pfizer and Moderna, are already at work adapting their coronavirus shots to the newly identified variant. Facing a coronavirus variant t...
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Atea, Roche change plans for oral COVID-19 drug after trial setback

Atea's fast ascent last year was due to its plan to use a pill originally developed for hepatitis C infections as a treatment for COVID-19. The strategy resonated wit...
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Sanofi claims positive early data for mRNA COVID shot, but pivots to flu instead

When drugmakers geared up to respond to the pandemic, Sanofi and GSK, as two of the largest vaccine makers, were expected to make a major contribution. Protein-based ...
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Regeneron drug extends survival in lung cancer trial, lifting company’s hopes in field

Since its first approval in first-line lung cancer in 2016, Keytruda has proved a tough competitor for rival drugmakers to challenge with their own therapies. Bristol...
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FDA rejects a biotech’s kidney drug, but some analysts still see a ‘sliver of hope’

The FDA's decision wasn't surprising to analysts, as "deficiencies" in an approval application have become somewhat of a prelude to rejection. This year alone saw two...
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