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Cell and Gene Therapy

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Volume 6 Issue 2

Essential Considerations for a Successful Submission under EU CTR

The European Union Clinical Trials Regulation (EU CTR), which came into force in January 2022, was the biggest change to EU medicinal product legislation since 1995 w...
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Volume 6 Issue 2

Augmenting Inspiration with Generative Chemistry

The ability of computers to produce new compound structures using ‘generative chemistry’ algorithms is a hot topic in drug discovery. The field has recently been rein...
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Volume 6 Issue 2

Utilising Size Selection to Enhance Gene Synthesis in Synthetic Biology Workflows

Biotechnology harnesses cellular and biomolecular processes to develop technologies and products. These products already improve our lives and show great potential fo...
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Volume 6 Issue 2

CSOs in CDMOs giving mRNA Manufacturing Considerations

Standard and Practical Process to Fast-Track mRNA Drug Product Manufacturing The central dogma of life has DNA on one side, protein on the other, and RNA sitting rig...
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Volume 6 Issue 2

Are We Ready to Formulate the Next Generation of Small Targeted Therapeutics?

The drug discovery pipeline is currently bursting with innovative small and medium sized modalities and targeted therapies. Progress in molecular biology and genome s...
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Volume 6 Issue 2

Cell Therapy: Challenges and Perspectives

The achievements of cell-based therapeutics over the last decades have bolstered efforts in recent years to bring more of these products to market and across an ever ...
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Volume 6 Issue 2

Recreating Life in the Lab: How Predictive Human Organ Models are Transforming the Efficiency of Drug Discovery

An often-underreported fact within the drug discovery and development industry is that around 90% of drug candidates reaching clinical trials ultimately fail, with an...
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Volume 6 Issue 2

Go-to-market Challenges of CAR-T Therapies

CAR-T therapies are set to revolutionise cancer treatment. With the first curative therapies gaining market access across the globe, CAR-T therapies are subject to nu...
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