Biotherapeutic production relies on robust cell lines with reproducible growth, titre and quality, so determining the titre of biopharmaceuticals at multiple points during the production process is valuable. Analytical testing of cell culture in monoclonal antibody (mAb) production calls for rapid, robust antibody titre measurements with a wide dynamic range, to monitor product yields throughout a bioreactor run. Kurt Pickle at IDEX Health & Science explains that as well as a wide dynamic range and robustness, accuracy, speed and specificity are critical parameters in titre measurements.

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