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Essential DMPK Approaches for IND Success

Ninety per cent of drug candidates that enter clinical trials never reach patients. Developing a single new medicine now costs more than a billion dollars. Too o...
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From Signal to Standard: The Rising Structural Role of Biomarkers in Oncology Trials

From Afterthought to Design Driver Over the past decade, biomarkers have moved from the margins of oncology clinical trials into their structural core. Where ...
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Turning Oncology Data into Better Development Decisions

Oncology remains one of the highest-attrition areas in drug development, with only a small minority of candidates entering clinical testing going on to reach app...
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When the Gene Editing Guide is the Drug

The rapid evolution of gene therapies and gene editing modalities in particular is challenging how personalised medicines are developed and evaluated. Many rare ...
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From Cell Culture to Human-Relevant Models

Every generation of mammalian cell culture has solved one biological challenge while revealing the next. The earliest researchers sought to keep living cells ali...
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