PCI 7 November 2023, 15:22
Thermofisher: Thu 29 February 2024, 11:15
BMG Labtech: Wed 18 September 2024, 11:55
Owen Mumford 12 January 2022, 16:46

Current Edition

Cell and Gene Therapy

Upcoming Events

NextGen BioMed – 04/02/2025
BioTrinity 2025 – January 30th 2025
Elrig R&I 2025 – 27th January 2025
Biotechnology Show 2025: 20th January 2025
Anglonordic: 16th January 2025
AI in Drug Discovery – SAE media – January 14th 2025

Advertisement

Fujifilm rectangle: Fri 22 November 2024, 14:23
Roald Dahl Charity: Fri 15 November 2024, 12:57
A&M STABTEST: Fri 21 June 2024, 11:43
CDD Vault: Wed 17 July 2024, 11:46
Aurisco – 04/02/2025

Elpis Biomed Human Cell Models Could Potentially Replace Animal Experiments in Drug Discovery

Cambridge, UK, October 25, 2018 / B3C newswire / — Elpis Biomed Ltd. (Elpis), a University of Cambridge spin-out developing high quality human cells via its proprietary OPTi-OX platform, is pleased to announce that life science entrepreneur Dr Jonathan Milner, Deputy Chairman and Founder of Abcam, mentioned the Company, stating: “Elpis human cells can fix the broken drug discovery process by replacing animal experiments,” during his plenary lecture at the recent European Laboratory Research & Innovation Group (ELRIG) Drug Discovery Conference.

During his plenary address, on ‘Opportunities in the Golden Age of Biology’, Dr Milner asked whether the drug discovery process is ‘broken’. Dr Milner explained: “Over the past decades, the return on investment on pharmaceutical research and development has suffered exponential decline. A main contributor to the rising costs of drug development are high failure rates, both at the pre-clinical and clinical stage.” He continued: “The causes for drug failure are likely due to the biological differences between the current animal models and cell lines used for drug discovery and human biology. The solution to this problem is to integrate human cell models early into the drug development process.”

Although human cells are better models for drugs screening, few were featured at the ELRIG conference. Dr Milner commented, “The lack of human cell models being utilised boils down to the fact that the current technology for generating patient derived cells does not meet the requirements for drug screening.” Elpis, backed by Milner’s personal investment, “provides the first robust and scalable solution of functional biologically-relevant cells for drug development,” he added.

Further technical details of Elpis’s OPTi-OX platform are described in the peer-reviewed paper by Pawlowski et at, entitled Pluripotent Stem Cells into Neurons, Skeletal Myocytes, and Oligodendrocytes in Stem Cell Reports, 2017, 8 (4):803-812.

Dr Mark Kotter, scientific founder of Elpis BioMed concluded: “Elpis’ mission is to make human cells easy.  Our proprietary OPTi-OX technology allows us to produce human cells of unprecedented quality, purity, and consistency.  We are developing a wide range of cell products to support the research, drug discovery, and cell therapy communities and are delighted that our technology has been brought to the attention of an audience of drug discovery experts by an industry heavy-weight like Dr Milner.”

Newcells 3 June 2024, 15:12
Novonordisk: Wed 17 July 2024, 11:22
FujiFilm 30 October 2023, 16:23
Autoscribe Mon 26 June 2023, 15:15
Aldevron: 16th January 2025
Richter: Wed 23 October 2024, 09:03
GenXPro: Mon 16 September 2024, 10:40