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Non-clinical Safety Evaluation of Vaccine: Strategic Considerations to Accelerate Clinical Development

Vaccines are medicinal products intended to elicit (an) immune response(s) that can prevent (prophylactic vaccine) and/or lessen the severity (therapeutic vaccine) of a given disease. Dr. Sebastian Joseph at PharmaLex explains how vaccination involves priming the immune system of a host with an infectious agent or components of an infectious agent, modified in a manner to ensure that the vaccine does not cause any harm or disease to the host, but ensures that when the host is confronted with that infectious agent, its immune system can respond adequately to control the invading organism before it causes any ill effect.

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