PCI 7 November 2023, 15:22
Thermofisher: Thu 29 February 2024, 11:15
BMG Labtech: Wed 18 September 2024, 11:55
Owen Mumford 12 January 2022, 16:46

Current Edition

Cell and Gene Therapy

Upcoming Events

PEGS Boston – 17/02/2025
NextGen BioMed – 04/02/2025
BioTrinity 2025 – January 30th 2025
Elrig R&I 2025 – 27th January 2025
Biotechnology Show 2025: 20th January 2025
Anglonordic: 16th January 2025
AI in Drug Discovery – SAE media – January 14th 2025

Advertisement

Fujifilm rectangle: Fri 22 November 2024, 14:23
Roald Dahl Charity: Fri 15 November 2024, 12:57
A&M STABTEST: Fri 21 June 2024, 11:43
CDD Vault: Wed 17 July 2024, 11:46
Aurisco – 04/02/2025

Removing bubble trouble from micro and nanofluidic systems

Biotech Fluidics has developed low volume online degassing modules for micro- and nanofluidic systems used for life science applications including dispensing, diagnostics, drug screening, nucleic acid sequencing and tissue culture.

In most micro- and nanofluidic systems, the formation and accumulation of air or gas bubbles can be severely detrimental to their operation. Once a bubble is generated, it is also extremely difficult to remove. The presence of bubbles can cause aggregation problems with particles or proteins, can damage chemical functionalization of surfaces, and in cell culture, bubbles can lead to cellular death.

DEGASi® PLUS MICRO low volume degasser

Robin Oz, degassing product specialist at Biotech Fluidics, commented “We have observed how a single gas bubble in micro and nano liquid dispensers can impair their dispensing precision and accuracy. Removing dissolved gases from liquids prior to dispensing eliminates the risk of having bubbles in the fluidic channels”.

He added “Another microscale application where liquid degassing is crucial is Surface Plasmon Resonance (SPR) analysis. The sensing mechanism in SPR is heavily based on interactions between analyte and a functionalized surface. A bubble will create an obstruction on the surface, resulting in an irregular and non-specific signal and creating an abnormality in the resulting sensogram. Installing a low volume DEGASI onlinedegassing module prior to liquid introduction to the SPR system completely negates this gas bubble problem”.

The DEGASi® PLUS MICRO from Biotech Fluidics is a low volume (100 µl per channel) degasser specifically designed for SPR and other micro- and nanofluidic system applications. The system removes dissolved gases from the mobile liquid phase thereby eliminating bubbles before they occur and removes oxygen which can interfere with UV detection methods. The system is available in 1-6 channel versions.

To discuss how to degas your micro- or nano fluidic application please contact Biotech Fluidics on + 46 300 56 91 80 / + 612-703-5718 / robin.oz@biotechfluidics.com.

For further information on the DEGASi® PLUS MICRO degasser please visit https://www.biotechfluidics.com/product/biotech-degasi-plus-micro-stand-alone-degasser-1-channel-100-%C2%B5l-systec-af/.

Media: Bill Bradbury (tel. +44-208-546-0869 / email info@primetek-solutions.com)

Technical: Robin Oz  (tel. +46-300-569180 / email robin.oz@biotechfluidics.com)

Newcells 3 June 2024, 15:12
Novonordisk: Wed 17 July 2024, 11:22
FujiFilm 30 October 2023, 16:23
Autoscribe Mon 26 June 2023, 15:15
Aldevron: 16th January 2025
Richter: Wed 23 October 2024, 09:03
GenXPro: Mon 16 September 2024, 10:40