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Volume 7 Issue 4
Cell and Gene Therapy

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The Science is Stacking Up for Regenerative Medicine
Volume 4 Issue 1

The Science is Stacking Up for Regenerative Medicine

New Data Shows Positive Potential for Osteoarthritis Treatment in Knees A new peer-reviewed paper published in a special issue of Stem Cells International evidences ...
30 March 2021 Volume 4 Issue 1
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Biosimilars – Increasing Regulatory Focus on Orthogonal Analytical Characterisation
Volume 4 Issue 1

Biosimilars – Increasing Regulatory Focus on Orthogonal Analytical Characterisation

The COVID-19 pandemic has focused attention upon global pharmaceutical industries, and will continue to do so for some time to come. However, despite the initial disr...
30 March 2021 Volume 4 Issue 1
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Exploiting Epigenetics to Systematically Optimise Culture Conditions for Cellular Therapies
Volume 4 Issue 1

Exploiting Epigenetics to Systematically Optimise Culture Conditions for Cellular Therapies

One of the main challenges of cell therapies is the maintenance and/or expansion of the required therapeutic phenotype in vitro. Moreover, to meet both the traceabili...
30 March 2021 Volume 4 Issue 1
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Developments in Non-invasive Preclinical Lung Imaging to Support Drug Discovery
Volume 4 Issue 1

Developments in Non-invasive Preclinical Lung Imaging to Support Drug Discovery

Growing demand for safe, effective medicines for pulmonary disorders and diseases has increased the research into their treatment. This is key to discovering how to e...
30 March 2021 Volume 4 Issue 1
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Why Patient Diversity in Research Must Become the Norm
Volume 4 Issue 1

Why Patient Diversity in Research Must Become the Norm

While 2020 was not the year anyone hoped it would be, it did succeed in showing us what medical research can achieve when the life sciences sector works together to o...
30 March 2021 Volume 4 Issue 1
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Automated Identification of Cardiac Hypertrophy Modulators Using a hipsc-derived Disease Model
Volume 4 Issue 1

Automated Identification of Cardiac Hypertrophy Modulators Using a hipsc-derived Disease Model

Effective drug discovery and development rely heavily on the availability of predictive pre-clinical models. For decades, target-based drug discovery has focused on i...
30 March 2021 Volume 4 Issue 1
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Live Cell Imaging: Non-invasive Kinetic Data to Better Understand Cell Viability
Volume 4 Issue 1

Live Cell Imaging: Non-invasive Kinetic Data to Better Understand Cell Viability

The current assessment of cell viability depends on endpoint measurements. Unfortunately, this ignores the levels and rates of in-between measurements. However, advan...
30 March 2021 Volume 4 Issue 1
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Unlocking the Biomarker Revolution in Clinical Trials
Volume 4 Issue 1

Unlocking the Biomarker Revolution in Clinical Trials

Completion of the first human genome sequence exactly 20 years ago opened up the tantalising prospect of a new era of precision treatments, with accurate genetic diag...
30 March 2021 Volume 4 Issue 1
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Maximising mAbs Purification Efficiency: Focus Areas for Reducing Bottlenecks in Downstream Processing
Volume 4 Issue 1

Maximising mAbs Purification Efficiency: Focus Areas for Reducing Bottlenecks in Downstream Processing

Finding ways to remove bottlenecks and improve yields in downstream processing for monoclonal antibodies (mAbs) continues to be a key focus area for biopharma manufac...
30 March 2021 Volume 4 Issue 1
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High-throughput Sequencing Technologies are Revolutionising Antibody Discovery
Volume 4 Issue 1

High-throughput Sequencing Technologies are Revolutionising Antibody Discovery

Therapeutics based on antibodies (Abs) are at the forefront of revolutionary treatments for cancer, autoimmunity and many other diseases. The application of high-thro...
30 March 2021 Volume 4 Issue 1
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